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medication side effects From 2000 to 2010, a total of 142 melanoma, 580 SCC, and 3030 BCC cases were documented. Recent sildenafil users at baseline had a significantly elevated risk of invasive melanoma with multivariate-adjusted HR of 1.84 (95% CI, 1.04-3.22). In contrast, we did not observe a significantly altered risk of SCC or BCC associated with sildenafil use; the HR was 0.84 (95% CI, 0.59-1.20) for SCC and 1.08 (0.93-1.25) for BCC (Table 2). Ever use of sildenafil was also associated with a higher risk of melanoma (HR,?1.92; 95% CI, 1.14-3.22) (eTable 1 in the Supplement). In addition, controlling for the history of major chronic diseases did not change the results appreciably (data not shown).1. Cerner Multum, Inc. "Australian Product Information." O 0
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